What Is the Difference Between Neurotoxins: Botox, Dysport, Xeomin, Jeuveau, Daxxify?

Neurotoxin treatments are one of the most popular ways to soften fine lines and wrinkles—but not all neurotoxins are the same. While they all work by temporarily relaxing targeted facial muscles, each product has unique characteristics that affect how quickly it works, how long it lasts, and how it feels. At Aesthetistry Med Spa, we choose neurotoxins strategically based on your anatomy, goals, and desired results.

How Neurotoxins Work (In Simple Terms)

All FDA-approved neurotoxins are derived from botulinum toxin type A. They temporarily block nerve signals to specific muscles, preventing repetitive movements that cause dynamic wrinkles such as:

• Forehead lines

• Frown lines (11s)

• Crow’s feet

• Advanced injection techniques can target other areas of concern

The result is smoother skin and a more refreshed appearance—without surgery.

Main Types of Neurotoxins and Difference Between Them

Botox®

Best known | First on the market

• Onset: 3–7 days

• Longevity: 3–4 months

• Feel: Firm, structured hold

• Best for:

  • Strong muscle movement

  • Forehead lines and frown lines

  • High indication profile list

Why clients choose it: Predictable results with a long-standing safety record.

Dysport®

Faster onset | Softer spread

• Onset: 2–3 days

• Longevity: 3–4 months

• Feel: Softer, more diffused

• Best for:

  • Larger treatment areas (forehead)

  • Clients who want a more natural movement

  • Faster results

Why clients choose it: Natural look with quicker visible results.

Xeomin®

“Naked” neurotoxin | Pure formulation

• Onset: 3–5 days

• Longevity: 3–4 months

• Feel: Clean, precise

• Best for:

  • Clients who may build resistance

  • Those sensitive to additives

  • Precision treatments

Why clients choose it: No accessory proteins—just the active ingredient.

Jeuveau®

Modern formula | Aesthetic-focused

• Onset: 3–5 days

• Longevity: 3–4 months

• Feel: Balanced and smooth

• Best for:

  • Younger clients

  • Preventative treatments

  • Cost-conscious patients

Why clients choose it: Designed specifically for cosmetic use.

Daxxify®

Longest-lasting option

• Onset: 1–2 days

• Longevity: 5–9 months

• Feel: Strong, long hold

• Best for:

  • Clients wanting fewer appointments

  • Deep or strong muscle activity

Why clients choose it: Extended duration with fewer treatments per year.

Which Neurotoxin Is Right for You?

There’s no one-size-fits-all answer. The best neurotoxin depends on:

• Your facial anatomy

• Muscle strength

• Desired level of movement

• How quickly you want results

• How long you want them to last

At Aesthetistry Med Spa, we often customize treatment using different neurotoxins based on patient preference and desired outcome to achieve the most natural, refreshed look .

Do All Neurotoxins Look the Same?

No—the injector’s skill matters more than the brand.

A conservative, artistic approach ensures:

✔ Natural facial expressions

✔ Balanced symmetry

✔ No “frozen” look

✔ Results tailored to your face

Final Thoughts

Neurotoxins are powerful tools for both prevention and rejuvenation—but choosing the right one makes all the difference.

A personalized consultation at Aesthetistry Med Spa will help you understand what the difference is between neurotoxins and ensures you receive the neurotoxin that best fits your goals—not just the most popular name.

Book your neurotoxin consultation today!